Follow the Monomer
نویسنده
چکیده
Capping proteins limit actin filament growth, but paradoxically increase actin-based cell motility. This has been attributed to funneling of actin monomers to the filament ends that remain uncapped. Using a reconstituted motility system, Akin and Mullins (2008) now demonstrate that filament capping increases Arp2/3-based nucleation and branching, rather than elevating the rate of filament elongation.
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ورودعنوان ژورنال:
- Cell
دوره 133 شماره
صفحات -
تاریخ انتشار 2008