Follow the Monomer

نویسنده

  • James E. Bear
چکیده

Capping proteins limit actin filament growth, but paradoxically increase actin-based cell motility. This has been attributed to funneling of actin monomers to the filament ends that remain uncapped. Using a reconstituted motility system, Akin and Mullins (2008) now demonstrate that filament capping increases Arp2/3-based nucleation and branching, rather than elevating the rate of filament elongation.

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عنوان ژورنال:
  • Cell

دوره 133  شماره 

صفحات  -

تاریخ انتشار 2008